While the Common Mechanism provides robust DNA synthesis screening capabilities, the software currently has a few limitations users should be aware of:

• Processing speed: When running comprehensive searches using NCBI databases, the software may require significant processing time depending on your computational resources.

• Database size requirements: The software depends on large reference databases (~600 GB for standard protein and nucleotide databases), which may present storage challenges for some users.

• Oligonucleotide handling: The system does not currently have specialized functionality for screening oligo orders.

• Scope: The Common Mechanism is focused solely on sequence screening and does not provide customer screening capabilities. For guidance on customer screening, please refer to our customer legitimacy verification guidelines.

IBBIS is constantly working on reducing these limitations, which should gradually disappear as new updates are released.